Acquired Von Willebrand Disease
What is acquired von Willebrand disease?
Acquired von Willebrand disease is a rare bleeding disorder that might be caused by other medical problems or medicines. It prevents blood from clotting properly. It is rarer than the inherited form of von Willebrand disease.
What causes it?
Medical problems that might cause acquired von Willebrand disease include:
Rarely, acquired von Willebrand disease may also develop in direct association with use of certain medicines. When use is discontinued, signs of the disease also end. These medicines include:
- Ciprofloxacin.
- Griseofulvin.
- Valproic acid.
What are the symptoms?
Symptoms include nosebleeds or other unexplained bleeding with no previous history of bleeding abnormalities.
How is acquired von Willebrand disease treated?
Treatment of acquired von Willebrand disease includes medicines that help your body have enough von Willebrand clotting factor in the blood. This von Willebrand factor helps your blood clot. Your doctor will also treat the underlying cause of acquired von Willebrand disease if possible.
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Current as of: October 7, 2025
Current as of: October 7, 2025